75.48USD-1.91%Mkt Cap: 12.49B USDP/E: —Last update: 2026-06-01
Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemi…
Industry Peers
Biotechnology111.39BUSDP/E 26.0
100.62BDKKP/E 19.4
62.97BUSDP/E 14.7
48.39BEURP/E 31.7
44.65BEURP/E 37.2
40.10BUSDP/E 75.3
35.22BUSD—
32.91BSEKP/E 48.6
Indicators:|
Key Statistics
Company
Market Cap12.49B USD
Enterprise Value13.28B USD
Revenue (TTM)1.06B USD
Gross Profit927.80M USD
Net Income (TTM)-381.39M USD
Revenue/Share6.550 USD
Last Price75.48 USD
Fiscal Year EndDec 2025
MR QuarterMar 2026
Employees1.4K
CountryUS
SectorHealthcare
IndustryBiotechnology
ISINUS4622221004
Valuation
P/E (Trailing)—
P/E (Forward)-123.01
PEG27.33
EV/EBITDA-39.20
EV/Revenue12.55
P/S11.95
P/B25.83
EPS (TTM)-2.01
EPS (Forward)-0.62
52W Range
32.5579% of range86.74
52W High86.74 USD
52W Low32.55 USD
Profitability
Gross Margin98.31%
Oper. Margin-47.72%
EBITDA Margin-32.00%
Profit Margin-40.41%
ROE-77.98%
ROA-10.82%
Growth
Revenue Growth87.00%
Earnings Growth—
Cash Flow & Leverage
Operating CF-268.58M USD
CapEx (TTM)57.08M USD
FCF Margin-76.34%
FCF Yield-6.47%
Net Debt632.58M USD
Net Debt/EBITDA-1.87
Balance Sheet
Debt/Equity4.22
Current Ratio4.10
Quick Ratio2.86
Book Value/Sh2.962 USD
Cash/Share11.96 USD
Dividends
Fwd Div Rate—
Trail. Div Rate0.0000 USD
Div. Yield—
5Y Avg Yield—
Payout Ratio0.00%
Ex-Div Date—
Pay Date—
Analyst Consensus
Rating1.7 (Buy)
Target (Mean)100.92 USD
Target Range47.00 USD – 130.00 USD
# Analysts25
Ownership
Shares Out.165.26M
Float163.98M
Insiders0.61%
Institutions107.20%
Short Interest
Short Ratio8.9d
Short % Float12.91%
Short % Out.9.73%
Shares Short16.09M
Short (prev mo.)13.76M
Technical
SMA 5074.53 (+1.3%)
SMA 20072.71 (+3.8%)
Beta0.38
S&P 52W Chg27.94%
Avg Vol (30d)1.66M
Avg Vol (10d)1.78M
Technical Indicators
RSI (14)56.1
MACD0.4526
MACD Signal0.2128
MACD Hist.+0.2398
BB Upper78.14 USD
BB Middle75.68 USD
BB Lower73.22 USD
BB Width6.50%
ATR (14)2.232 USD
Vol Ratio (20d)0.36x