SPRB — Spruce Biosciences, Inc.

SPRBSpruce Biosciences, Inc.

NAS · US · Healthcare · Biotechnology · sprucebio.com

50.59USD+2.33%Mkt Cap: 140.78M USDP/E: —Last update: 2026-06-01

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human a…

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Indicators:|

Key Statistics

Company

Market Cap140.78M USD

Enterprise Value95.59M USD

Revenue (TTM)—

Gross Profit-13.62M USD

Net Income (TTM)-38.97M USD

Revenue/Share—

Last Price50.59 USD

Fiscal Year EndDec 2025

MR QuarterMar 2026

Employees8

CountryUS

SectorHealthcare

IndustryBiotechnology

ISIN—

Valuation

P/E (Trailing)—

P/E (Forward)82.69

PEG—

EV/EBITDA-3.70

EV/Revenue—

P/S—

P/B1.65

EPS (TTM)-35.82

EPS (Forward)0.62

52W Range

7.0005% of range838.13

52W High838.13 USD

52W Low7.000 USD

Profitability

Gross Margin0.00%

Oper. Margin0.00%

EBITDA Margin0.00%

Profit Margin0.00%

ROE-91.65%

ROA-73.49%

Growth

Revenue Growth—

Earnings Growth—

Cash Flow & Leverage

Operating CF-33.33M USD

CapEx (TTM)—

FCF Margin—

FCF Yield-9.36%

Net Debt-47.28M USD

Net Debt/EBITDA1.83

Balance Sheet

Debt/Equity0.02

Current Ratio4.67

Quick Ratio4.59

Book Value/Sh30.99 USD

Cash/Share19.65 USD

Dividends

Fwd Div Rate—

Trail. Div Rate0.0000 USD

Div. Yield—

5Y Avg Yield—

Payout Ratio0.00%

Ex-Div Date—

Pay Date—

Splits

Last Split1:75

Split DateAug 7, 2025

Analyst Consensus

Rating1.2 (Strong Buy)

Target (Mean)168.00 USD

Target Range120.00 USD – 230.00 USD

# Analysts5

Ownership

Shares Out.2.75M

Float2.65M

Insiders3.51%

Institutions31.06%

Short Interest

Short Ratio2.7d

Short % Float7.90%

Short % Out.7.81%

Shares Short215.06K

Short (prev mo.)180.54K

Technical

SMA 5059.18 (-14.5%)

SMA 20068.77 (-26.4%)

Beta—

S&P 52W Chg27.70%

Avg Vol (30d)74.75K

Avg Vol (10d)58.00K

Technical Indicators

RSI (14)39.5

MACD-2.7348

MACD Signal-2.4223

MACD Hist.-0.3125

BB Upper61.85 USD

BB Middle54.26 USD

BB Lower46.68 USD

BB Width27.95%

ATR (14)3.799 USD

Vol Ratio (20d)0.59x