UPBUpstream Bio, Inc.
8.100USD-3.69%Mkt Cap: 440.26M USDP/E: Last update: 2026-06-01

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of sev…

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Key Statistics

Company
Market Cap440.26M USD
Enterprise Value161.49M USD
Revenue (TTM)3.32M USD
Gross Profit3.32M USD
Net Income (TTM)-143.44M USD
Revenue/Share0.0610 USD
Last Price8.100 USD
Fiscal Year EndDec 2025
MR QuarterMar 2026
Employees75
CountryUS
SectorHealthcare
IndustryBiotechnology
ISIN
Valuation
P/E (Trailing)
P/E (Forward)-2.77
PEG
EV/EBITDA-0.94
EV/Revenue48.61
P/S136.95
P/B1.33
EPS (TTM)-2.90
EPS (Forward)-3.02
52W Range
7.2503% of range33.68
52W High33.68 USD
52W Low7.250 USD
Profitability
Gross Margin100.00%
Oper. Margin-4218.09%
EBITDA Margin0.00%
Profit Margin-5026.03%
ROE-42.22%
ROA-40.55%
Growth
Revenue Growth82.70%
Earnings Growth
Cash Flow & Leverage
Operating CF-133.28M USD
CapEx (TTM)165.00K USD
FCF Margin-2718.57%
FCF Yield-20.51%
Net Debt-293.47M USD
Net Debt/EBITDA1.71
Balance Sheet
Debt/Equity0.00
Current Ratio23.14
Quick Ratio21.74
Book Value/Sh6.264 USD
Cash/Share5.413 USD
Dividends
Fwd Div Rate
Trail. Div Rate0.0000 USD
Div. Yield
5Y Avg Yield
Payout Ratio0.00%
Ex-Div Date
Pay Date
Analyst Consensus
Rating1.5 (Buy)
Target (Mean)42.43 USD
Target Range15.00 USD75.00 USD
# Analysts7
Ownership
Shares Out.54.42M
Float35.01M
Insiders14.88%
Institutions90.10%
Short Interest
Short Ratio6.3d
Short % Float9.63%
Short % Out.6.24%
Shares Short3.40M
Short (prev mo.)3.02M
Technical
SMA 509.189 (-11.9%)
SMA 20018.36 (-55.9%)
Beta
S&P 52W Chg27.70%
Avg Vol (30d)490.11K
Avg Vol (10d)585.19K
Technical Indicators
RSI (14)41.6
MACD-0.3437
MACD Signal-0.3380
MACD Hist.-0.0057
BB Upper9.640 USD
BB Middle8.771 USD
BB Lower7.902 USD
BB Width19.82%
ATR (14)0.5019 USD
Vol Ratio (20d)0.50x